Florfenicol is a spectroscopy antibiotic of chloramphenicol. It has a broad spectrum of antibacterial activity and is sensitive to most Gram-positive bacteria, Gram-negative bacteria and mycoplasma, among which Gram-negative bacteria are more effective. It is ideal for common bacteria such as Haemophilus parasuis, Actinobacillus pleuropneumoniae, Pasteurella, and Salmonella. However, there are a few points to be aware of when using florfenicol to raise the pig's efficacy. The following are the precautions for the use of florfenicol in the work of Hui Nongwang Xiaolin. I hope that I can help farmers who are raising pigs and friends who are interested in this issue! The antibacterial mechanism of florfenicol: By inhibiting peptide acyltransferase, peptide chain elongation is blocked, thereby inhibiting protein synthesis and achieving bacteriostatic action. Precautions for the use of florfenicol: 1, florfenicol has embryotoxicity, so pregnant animals are banned. Due to its extensive antibacterial spectrum, florfenicol is often used as a health care drug by aquaculture friends, but it must be noted that pigs can only be used for nursery or fat pigs. 2. Florfenicol is antagonistic to macrolides and lincosamide antibiotics. Clinically, florfenicol is often used together with tilmicosin or florfenicol with lincomycin to prevent and control piglet parasitic haemophilus, streptococcal disease and infectious pleuropneumonia. Waiting for the disease. However, from a pharmacological point of view, the mechanism of action of the two is very similar (macrolides and lincosamides inhibit protein replication by acting on the 50s subunit P unit), and there is competitive antagonism. Therefore, it is not recommended to use the above scheme. 3. Florfenicol is antagonistic to β-lactams and quinolones. Florfenicol is a fast-acting antibacterial agent, and β-lactam is a bactericidal drug in the breeding period. Both are antagonistic. Under normal circumstances, they cannot be used at the same time. However, quinolones are quiescent bactericides. In theory, the two have synergistic effects, but florfenicol can not be used together with aminoglycosides and quinolones. 4, florfenicol and doxycycline synergy. Doxycycline is a drug that works synergistically with florfenicol. In general, florfenicol can be used alone or with doxycycline or alone, and attention should be paid to the use of pigs. Biologics are drugs made from complex molecules manufactured using living microorganisms, plants, or animal cells.Anti-rabies Vacine for Human is a preparation of rabies fixed virus CTN-1V inoculated into Vero cell , which is used for the prevention of the rabies disease. Biological Product,Rabies Symptoms Human,Human Rabies Symptoms,Human Rabies Signs Changchun Zhuoyi Biological Co., Ltd , https://www.zhuoyi-bio.com
