Release date: 2015-07-31 Researchers at the National Institutes of Health in Maryland reported that they have developed a potential Middle East Respiratory Syndrome Coronavirus (MERS-CoV) vaccine. In mouse and macaque experiments, the new vaccine demonstrated the ability to immunize the virus against the Jordan N3 strain. Since the discovery of the Middle East Respiratory Syndrome Coronavirus in 2012, the number of cases has exceeded 1,000, and more than 400 deaths have been reported. People don't know much about how this virus spreads. Studies on viral hosts have not yet been confirmed, and there are still no effective treatments for respiratory diseases in which the virus produces severe symptoms in humans. In the new study, Kang Yongbiao and Bonnie Graham of the National Institutes of Health and their research team infect animals with DNA encoding the viral protein, with the help of this shortened viral protein in rats and macaques. The body elicits a series of antibodies against the virus, which ultimately immunizes the experimental animals from the pneumonia caused by the MERS-CoV. Related papers are published online on the website of Nature-Communication. The researchers say the immunization strategy is the first attempt to spur antibodies against multiple structures of MERS-CoV. These structures are spread over the medial and lateral sides of the virus, and with this method, the likelihood that the virus will escape the immune system through mutation will be greatly reduced. In addition, this study is the first time this type of vaccine has been tested on an animal model of MERS-CoV, and the first MERS-CoV vaccine has been shown to protect non-human primates. effect. However, it should be noted that the progression of the Middle East Respiratory Syndrome Coronavirus in primates is much milder than in humans. Whether this vaccine is suitable for the human body and the production of antibodies by human body is still unclear, and its safety and effectiveness in humans remains to be verified. Source: Technology Daily Food Ingredients Shandong YingLang Chemical Co.,Ltd , https://www.sdylhgtrade.com