Antagonism of several feeds and veterinary drugs

Soybeans are rich in minerals like calcium and magnesium, which can bind with tetracycline or oxytetracycline, forming water-insoluble compounds that reduce the effectiveness of these antibiotics. Therefore, it's best to avoid feeding soybeans when administering these medications.

Bran is high in phosphorus but low in calcium, making it unsuitable for animals suffering from conditions like cartilage issues or rickets caused by calcium deficiency. Additionally, excessive phosphorus can interfere with iron absorption, so it should be avoided when treating iron-deficiency anemia.

Cottonseed cake can affect the absorption of certain vitamins, particularly fat-soluble ones. As a result, it should not be fed to animals undergoing treatment for vitamin deficiencies.

Sorghum contains higher levels of tannic acid, which can denature iron-based preparations and hinder iron absorption. This makes it unsuitable for animals being treated for iron-deficiency anemia.

Spinach is high in oxalic acid, which can bind with calcium in the digestive tract to form insoluble calcium oxalate. This reduces the availability of calcium, so it’s advisable to stop feeding calcium-rich supplements such as shell powder, bone meal, or eggshell powder when spinach is part of the diet.

Salt can decrease the effectiveness of streptomycin and may cause water retention in livestock and poultry, leading to edema. Therefore, salt should be limited or completely removed from the diet when treating animals with nephritis or when using streptomycin as a medication.

This information highlights the importance of considering dietary interactions when administering medications, ensuring that nutritional intake does not compromise treatment outcomes. Always consult with a veterinarian before making changes to an animal’s diet during medical treatment.

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