Adverse Drug Reactions Detection of Antibiotics Ranked First in Seven Times

The Provincial Drugs (Medical Devices) Adverse Reaction Monitoring Center recently announced the adverse drug reaction monitoring report from January to June this year: The province reported a total of 3471 adverse reactions, 55.95% of which involved antibiotics, ranking first. This is the shortest period of three and a half years, the seventh consecutive time antibiotics adverse drug reactions in our province "champion."

Since the establishment of the Provincial Drugs (Medical Devices) Adverse Reaction Monitoring Center in October 2006, statistics on the adverse reactions in the first half of the year will be announced in September each year, and statistics will be published in January of the following year. Statistics show that from January 2007 to June this year, 18384 cases were related to antibiotics in the adverse reaction reports received by the center. In addition, among the new and serious reports of adverse drug reactions in the statistics, antibiotics are always ranked first and second.

The so-called adverse drug reaction refers to the unqualified or unintended reaction of a qualified drug under normal usage and dosage. It does not include the reaction caused by unintentional or deliberate overdose of drug, and the reaction caused by inappropriate drug use, and also drugs. Quality has nothing to do. "The report of adverse reactions caused by antibiotics has been increasing year by year. On the one hand, it has been shown that the awareness of the medical institutions has increased, and on the other, antibiotics have been used too much and too much. This is worrying," said Li Yuanqi, director of the center.

So, how serious is the extent of antibiotic abuse? During the past week, the reporter visited a number of hospitals and many experts in Wuhan. Respondents invariably agreed with the fact that antibiotics were abused, and expressed their deep concern. Experts believe that antibiotics have made extremely important contributions in the struggle between humans and diseases, but objectively speaking, if we do not prevent the further development of abuse, antibiotics may cause catastrophic impact on humankind, which has continuously emerged in recent years. The more powerful "super bacteria" is the more and more severe warning.

data

80% of patients with infectious diseases abuse antibiotics

"In hospital injection rooms, more than 70% of patients are using antibiotics," said a pharmacy expert from a large hospital in Hankou. This data has been recognized by a number of hospital related experts, some experts said that many should not use antibiotics are also used, abuse has greatly increased the incidence of antibiotic adverse reactions and drug injury events.

According to a statistics from the World Health Organization, 50% of children in China suffer from cough and runny nose, and 50% use antibiotics. In outpatient flu patients, 75% use antibiotics, and the proportion of antibiotics used in surgical patients is as high as 90% or even 100%.

It was also learned that from the 1995 to 2007 disease classification survey, infectious diseases in China accounted for 49% of the total incidence of total disease, of which bacteria accounted for 18%-21% of all diseases. In other words, only 20% of patients really need antibiotics, and 80% are antibiotics.

Visits

The pharmacy is selling and the hospital is open

In the past few days, this reporter has visited several drug stores and hospitals in Wuchang and Hankou as patients, and found that antibiotics are basically in the state of “opening up and selling”.

Pharmacy: Recommending Advanced Antibiotics

At about 3 pm yesterday, at a pharmacy in the mouth of the mouth of Zhongshankou Avenue in Hankou, the reporter said that his throat was uncomfortable and the staff immediately recommended several cephalosporin antibiotics. Prices ranged from a few yuan to more than 20 yuan. Reporter said that cephalosporin efficacy is too strong, just want to buy an ordinary point, the staff said that ordinary anti-inflammatory drugs are slow, with poor efficacy.

In fact, according to the relevant regulations of the state, antibiotics are prescription drugs and must be prescribed by doctors. However, in most pharmacies in Wuhan, they are actually in the state of “selling”. In the past few days, the reporter visited nine pharmacies. In addition to the staff of the People’s Pharmacy Fruit Lake Store, it was clearly stated that the purchase of antibiotics requires a doctor’s prescription, and the rest are directly recommending antibiotics such as amoxicillin and cephalosporins to reporters.

Hospital: The pen is the antibiotic

On the afternoon of the 21st, in a hospital clinic in a hospital in the Jiang’an District, the reporter said the throat was not very comfortable. A 40-year-old male doctor asked the reporter to open his mouth. After flashing the flashlight for two or three seconds, he said that the throat inflammation of the reporter was heavy. A box of cefuroxime axetil was opened and the price was 22.6 yuan.

In fact, the reporter was diagnosed with a slightly red throat on that day by a doctor in a subordinate hospital. No need to take medicine, drink plenty of water and rest.

In the afternoon of the previous day, in a community health service center in Hongshan District, the reporter also complained that she was uncomfortable and may have a cold. A 30-year-old female doctor looked at the throat and asked if the reporter was allergic to penicillin. After receiving a negative reply, he opened a box of cephalexin capsules for a price of 6 yuan.

Over the past week, the reporter visited a total of eight medical institutions, including three tertiary A hospitals, two A hospitals, and three community health service centers. Doctors have prescribed antibiotics, including "lowest level". Amoxicillin capsules (penicillins), "most advanced" are cefpodoxime tablets (belonging to the third generation cephalosporins). In general, the higher the level, the better the antibacterial effect and the more expensive the price.