The difference between primary cells and cell lines

The biggest advantage of primary cell culture is that the cells are directly derived from the body tissues, and the biological traits have not undergone major changes, which can reflect the state of the body to a certain extent.

The cell line is not exactly the same as the primary cell.

Not every tissue-derived cell has a corresponding cell line, and some cells must be raised.

The cell line is derived from a primary cell, and the primary cell is introduced into a virus proliferating gene and transformed into a cell strain, which has the characteristics of a cancerous cell.

The genetic material of the cell line has changed and no longer has contact growth inhibition.

The morphology and state of the cell lines are not as good as those of the primary cells, and they are passaged for a relatively long time; while primary cell growth is limited.

The cell strain may undergo morphological changes and mutations during the passage, and the cell strain does not use primary cell stability.

The receptors of primary cells can correctly reflect the physiological and pathological state of the body.

The signaling signals of primary cells can correctly reflect the physiological and pathological state of the body.

The protein biological characteristics of primary cells can correctly reflect the physiological and pathological state of the body.

The biological characteristics of the primary cells can correctly reflect the physiological and pathological state of the body.

The DNA biology and genetic characteristics of primary cells can correctly reflect the physiological and pathological state of the body.

The response of the primary cells to the outside world can correctly reflect the physiological and pathological state of the body.

Primary cells can accurately reflect physiological and pathological conditions in vivo.

Primary cells have a toxic and teratogenic response that correctly reflects the physiological and pathological state of the body.

Primary cell screening for drugs can correctly reflect physiological and pathological conditions in the body.


Primary cells can correctly reflect the physiological and pathological state of the body in individualized drug treatment.

The primary cell culture is the same as the original structure of the body in terms of morphological structure and functional activities, and is definitely the best experimental object for detection and drug treatment.

For in vitro testing and drug development in China for cell culture, please use Chinese to organize primary primary cells.

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